Human Kidney eQTL Atlas
Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments
Publication related to the human kidney eQTL atlas:
Please cite following papers:
Kidney eQTL (meta-analysis in 686 individuals) by Liu et al. Nature Genetics 54, 950–962 (2022) eQTL(Meta)
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Hongbo Liu, Tomohito Doke, Dong Guo, Xin Sheng, Ziyuan Ma, Joseph Park, Ha My T. Vy, Girish N. Nadkarni, Amin Abedini, Zhen Miao, Matthew Palmer, Benjamin F. Voight, Hongzhe Li, Christopher D. Brown, Marylyn D. Ritchie, Yan Shu and Katalin Susztak |
Link to the paper: Liu, H. et al., Nature Genetics, 2022
Supplementary Data: Nature Genetics | figshare
Sequencing data on GEO database: GSE200547 | GSE172008
Customized code used in this study: Github
Cell fraction eQTL and cell type interaction eQTL studies by Sheng et al. Nature Genetics 53, 1322–1333 (2021) eQTL(cf) | eQTL(ci)
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Xin Sheng, Yuting Guan, Ziyuan Ma, Junnan Wu, Hongbo Liu, Chengxiang Qiu, Steven Vitale, Zhen Miao, Matthew J. Seasock, Matthew Palmer, Myung K. Shin, Kevin L. Duffin, Steven S. Pullen, Todd L. Edwards, Jacklyn N. Hellwege, Adriana M. Hung, Mingyao Li, Benjamin F. Voight, Thomas M. Coffman, Christopher D. Brown and Katalin Susztak |
Link to the paper: Sheng, X. et al., Nature Genetics, 2021
Supplementary Data: Nature Genetics | figshare
Sequencing data on GEO database: GSE173343 | GSE115098 | GSE172008
Customized code used in this study: Github
Bulk eQTL study by Qiu et al. Nature Medicine 24, 1721–1731 (2018) eQTL(b)
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Chengxiang Qiu, Shizheng Huang, Jihwan Park, YoSon Park, Yi-An Ko, Matthew J. Seasock, Joshua S. Bryer, Xiang-Xi Xu, Wen-Chao Song, Matthew Palmer, Jon Hill, Paolo Guarnieri, Julie Hawkins, Carine M. Boustany-Kari, Steven S. Pullen, Christopher D. Brown and Katalin Susztak |
Link to the paper: Qiu, C. et al., Nature Medicine, 2018
Supplementary Data: Nature Genetics
Sequencing data on GEO database: GSE115098